Myocardial Infarction: Cell Therapy for Cardiac Regeneration

Article Information

Article Type: Review Article

Citation: Bartulos O (2015) Myocardial Infarction: Cell Therapy for Cardiac Regeneration. J Hear Health, Volume1.1: http://dx.doi.org/10.16966/jhh.103

Copyright: © 2015 Bartulos O. This is an openaccess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 06 February, 2015.

 Accepted date: 12 March, 2015.

 Published date: 16 March 2015.

Author :
Oscar Bartulos : Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Internal Medicine Department, Yale University, New Haven, Connecticut, USA
Oscar Bartulos : Yale Stem Cell Center, Yale University, New Haven, Connecticut, USA

Abstract

Mortality rate in patients that suffer heart failure is approximately 50 per cent in a 5-year follow up, exceeding the mortality detected in patients with cancer. Angiotensin Converting Enzyme (ACE) inhibitors and beta-blockers are effective to treat Myocardial Infarction (MI), but there is no effective therapy to reverse the disease. In the last two decades, cell therapy has emerged as an important treatment to be considered for patients with MI. In the present Review, I will summarize the diversity of cell therapies that have been used in pre-clinical and clinical studies, discussing the pros and cons of each therapy.

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