Off-Label Indications for Transcatheter Aortic Valve Replacement: A Worrying Trend - Sci Forschen Inc.

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Aritcle Type: Short Communication

Citation: Hernandez-Vaquero D (2015) OffLabel Indications for Transcatheter Aortic Valve Replacement: A Worrying Trend. J Hear Health 1 (3): doi http://dx.doi.org/10.16966/2379-769X.113

Copyright: © 2015 Hernandez-Vaquero D. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 14 Sept 2015

 Accepted date: 28 Sept 2015

 Published date: 30 Sept 2015


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Robotic Radical Prostatectomy, Daycase Surgery and Cardiac Assessment- Pandora’s Box - Sci Forschen Inc.

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Aritcle Type: Letter to Editor

Citation: Goonewardene SS, Persad R (2015) Robotic Radical Prostatectomy, Daycase Surgery and Cardiac Assessment- Pandora’s Box. J Hear Health 1 (3): doi http://dx.doi. org/10.16966/2379-769X.112

Copyright: © 2015 Goonewardene SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 04 August 2015

 Accepted date: 03 Sep 2015

 Published date: 06 Sep 2015

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Sudden Cardiac Death in Athletes: Current Knowledge and Newer Concepts - Sci Forschen Inc.

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Aritcle Type: Research Article

Citation: Levy S, Peyrol M, Sbragia P (2015) Sudden Cardiac Death in Athletes: Current knowledge and Newer Concepts. J Hear Health 1 (3): doi http://dx.doi.org/10.16966/2379-769X.111

Copyright:© 2015 Levy S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 24 August 2015

 Accepted date: 08 Sep 2015

 Published date: 12 Sep 2015


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Ischemia-Reperfusion Injury of the Heart: Moving forward with our Knowledge - Sci Forschen Inc.

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Aritcle Type: Research Article

Citation: Ducas A, Bartekova M, Dhalla NS (2015) Ischemia-Reperfusion Injury of the Heart: Moving forward with our Knowledge. J Hear Health 1 (3): doi http://dx.doi.org/10.16966/2379- 769X.110

Copyright:© 2015 Ducas A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 29 July 2015

 Accepted date: 28 August 2015

 Published date: 2 September 2015


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Joint Effects of Serum 25(OH) D and C-Reactive Protein Concentration on Coronary Heart Disease and All-cause Mortality in Patients with Diabetes Mellitus

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Article Type:  Research

Citation: Longjian Liu (2015) Joint Effects of Serum 25(OH) D and C-Reactive Protein Concentration on Coronary Heart Disease and All-cause Mortality in Patients with Diabetes Mellitus. J Heart Health 1 (1): http://dx.doi.org/10.16966/jhh.105

Copyright:© 2015 Longjian Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 06 April, 2015

 Accepted date: 08 May, 2015

 Published date: 11 May, 2015.

Authors :
Longjian Liu : Department of Epidemiology and Biostatistics, and Department of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, PA, 19104, USACorresponding author: Longjian Liu, MD, PhD, MSc (LSHTM), FAHA, Interim Chair of the Department of Environmental & Occupational Health, Associate Professor, Department of Epidemiology & Biostatistics, Drexel University School of Public Health, RM 515, Nesbitt Hall, 3215 Market ST, Philadelphia, PA 19104, USA, Tel: 267-359-6049, 267-886-5138; E-mail: Longjian.Liu@Drexel.edu

Abstract

The study aimed to examine the joint predicting effect of serum 25(OH) D (a biomarker of vitamin D level in blood) and C-reactive Protein (CRP) concentration on the risk of mortality from Coronary Heart Disease (CHD) and all-causes in patients with type 2 Diabetes Mellitus (T2DM) using data from the third National Health and Nutrition Examination Survey (NHANES III). Of 14965 subjects aged ≥ 30 years who participated in the NHANESIII, 2146 patients with T2DM at baseline (1988-1994) were followed up through December 31 of 2006. The associations of baseline serum 25(OH) D and CRP with outcomes were examined prospectively using Cox’s hazard proportional regression models. The results show that during a median follow-up of 12.3 years, 1257 (58.6%) of the patients with T2DM died, and 370 deaths were from CHD. Multivariate adjusted Cox’s models indicate that decreased 25(OH) D level significantly predicted risk of death. The corresponding hazard ratios for the risk of CHD mortality among those with serum 25(OH) D levels 20-29.9, 10-19.9, and <10 ng/mL were 1.35, 1.38 and 2.19, as compared to those with 25(OH) D ≥ 30 ng/mL, respectively. Similar associations between decreased 25(OH) D and risk of all-cause mortality were observed. Furthermore, a joint effect of decreased 25(OH) D and increased CRP significantly predicted an increased risk of CHD and all-cause mortality. In conclusion, using data from a nationally representative and longitudinal survey, findings from the study suggest that decreased serum vitamin D and increased CRP concentrations significantly predicted the risk of CHD and all-cause mortality in patients with T2DM.

Keywords

Prospective Study; Vitamin D; Inflammation; Mortality

Figure 2: Joint effects of serum 25(OH) Dand CRP concentrations on CHD (Figure A) and all-cause (Figure B) mortality

Figure 1:Survival function of patients with T2DM died from CHD (Figure A) and all-causes (Figure B)
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Prospective ECG-triggering Coronary CT Angiography (CCTA): How Safe is this Procedure?

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Article Type: Review Article

Citation: Sabarudin A (2015) Prospective ECGtriggering Coronary CT Angiography (CCTA): How Safe is this Procedure? J Hear Health, Volume1.1: http://dx.doi.org/10.16966/jhh.104

Copyright: © 2015 Sabarudin A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history: 

 Received date: 12 March, 2015

 Accepted date: 24 March, 2015

 Published date: 28 March 2015

Authors :
Akmal Sabarudin : Diagnostic Imaging & Radiotherapy Programme, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, University Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia
Corresponding author: Dr. Akmal Sabarudin, Diagnostic Imaging & Radiotherapy Programme, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, University Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia, Tel: 603-9289 7641; Fax: 603-2692 9032; E- mail: akmal.sabarudin@ukm.edu.my

Abstract

With the rapid development of CT technology, the procedure of Coronary CT Angiography (CCTA) has been increasingly used and widely available for the diagnosis of Coronary Artery Disease (CAD). Other than having its advantages to improve the sensitivity and specificity in the detection of CAD, CCTA also associated with high radiation dose. Several dose-reduction strategies have been introduced to reduce radiation dose during CT procedure. However, one of the technique, namely prospective ECG-triggering CCTA provides tremendous radiation dose reduction to patient. Therefore, this article provides information on the prospective ECG-triggering technique and how it can further reduce the radiation dose to patient.

Keywords|
Coronary CT angiography; Coronary artery disease; Electro Cardiogram (ECG)

Figure 1: Variations in CCTA scanning techniques produced different radiation dose. In standard retrospective gating, the tube current is constantly ‘on’ throughout the acquisition produces high radiation dose while in prospective ECG-triggering, the exposure is ‘on’ at the selective cardiac phase (diastolic phase) for a short period resulting low radiation dose production.
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Myocardial Infarction: Cell Therapy for Cardiac Regeneration

Article Information

Article Type: Review Article

Citation: Bartulos O (2015) Myocardial Infarction: Cell Therapy for Cardiac Regeneration. J Hear Health, Volume1.1: http://dx.doi.org/10.16966/jhh.103

Copyright: © 2015 Bartulos O. This is an openaccess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 06 February, 2015.

 Accepted date: 12 March, 2015.

 Published date: 16 March 2015.

Author :
Oscar Bartulos : Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Internal Medicine Department, Yale University, New Haven, Connecticut, USA
Oscar Bartulos : Yale Stem Cell Center, Yale University, New Haven, Connecticut, USA

Abstract

Mortality rate in patients that suffer heart failure is approximately 50 per cent in a 5-year follow up, exceeding the mortality detected in patients with cancer. Angiotensin Converting Enzyme (ACE) inhibitors and beta-blockers are effective to treat Myocardial Infarction (MI), but there is no effective therapy to reverse the disease. In the last two decades, cell therapy has emerged as an important treatment to be considered for patients with MI. In the present Review, I will summarize the diversity of cell therapies that have been used in pre-clinical and clinical studies, discussing the pros and cons of each therapy.

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